Enhanced Validation

Monoclonal Anti-VGLUT1 Antibody

solute carrier family 17 member 7
References (10)
Recommended Applications
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Product Description
Monoclonal Antibody against Human SLC17A7
Alternative Gene Names
SLC17A7, BNPI
Open Datasheet
Price
$505.00
Product Number
AMAb91041
Unit Size
Concentration
Lot dependent
Availability
>10 in Stock
Ships
Ready to Ship
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[7 pictures]
Immunohistochemistry analysis in human cerebral cortex and tonsil tissues using AMAb91041 antibody. Corresponding VGLUT1 RNA-seq data are presented for the same tissues.
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[1 pictures]
Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10
Lane 2: Human Cerebral Cortex tissue

Human Protein Atlas

View this protein on the Human Protein Atlas
Target Protein
solute carrier family 17 member 7
Target Gene
SLC17A7
Belongs to Antibody Panel
Neuroscience Markers
Verified Species Reactivity
Human, Mouse, Rat
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000070570 (94%)

Rat ENSRNOG00000020650 (94%)

Clonality
Monoclonal
Clone ID
CL2754
Isotype
IgG2b
Host
Mouse
Buffer
40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Protein A purified
Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Concentration
Product Data Sheet
Download data sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:5000 - 1:10000

Retrieval method: HIER pH6

Western Blot (WB)

Recommended conditions:

Working concentration: 1 µg/ml

Protocols
View all protocols
Immunohistochemistry (IHC)

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

All IHC characterization data in 44 normal tissues and 20 cancers for AMAb91041 on the Human Protein Atlas
Western Blot (WB)

Validated in Western blot using relevant lysates (see Western blot application images above)

Protein Name
solute carrier family 17 member 7
Gene Name
SLC17A7
Alternative Gene Names
SLC17A7, BNPI
UniProt ID
Q9P2U7
Gene (Ensembl)
ENSG00000104888
Entrez Gene ID
Entrez gene: 57030
Shipping
Normally shipped at ambient temperature
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Pomierny B, Krzyżanowska W, Skórkowska A, Jurczyk J, Bystrowska B, Budziszewska B, Pera J

Inhibition of Vesicular Glutamate Transporters (VGLUTs) with Chicago Sky Blue 6B Before Focal Cerebral Ischemia Offers Neuroprotection

Mol Neurobiol , 2023 Feb 18; 60(6):3130-3146. Epub 2023 Feb 18

PubMed ID: 36802054 DOI: 10.1007/s12035-023-03259-1

Falconieri A, De Vincentiis S, Cappello V, Convertino D, Das R, Ghignoli S, Figoli S, Luin S, Català-Castro F, Marchetti L, Borello U, Krieg M, Raffa V

Axonal plasticity in response to active forces generated through magnetic nano-pulling

Cell Rep , 2022 Dec 29; 42(1):111912. Epub 2022 Dec 29

PubMed ID: 36640304 DOI: 10.1016/j.celrep.2022.111912

Lee WS, Al-Ramahi I, Jeong HH, Jang Y, Lin T, Adamski CJ, Lavery LA, Rath S, Richman R, Bondar VV, Alcala E, Revelli JP, Orr HT, Liu Z, Botas J, Zoghbi HY

Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1

J Clin Invest , 2022 May 2; 132(9):e156616. Epub 2022 May 2

PubMed ID: 35499073 DOI: 10.1172/JCI156616

Giehrl‐Schwab J, Giesert F, Rauser B, Lao CL, Hembach S, Lefort S, Ibarra IL, Koupourtidou C, Luecken MD, Truong DJ, Fischer‐Sternjak J, Masserdotti G, Prakash N, Ninkovic J, Hölter SM, Vogt Weisenhorn DM, Theis FJ, Götz M, Wurst W

Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons

EMBO Mol Med , 2022 Apr 4; 14(5):e14797. Epub 2022 Apr 4

PubMed ID: 35373464 DOI: 10.15252/emmm.202114797

Saberi A, Aldenkamp AP, Kurniawan NA, Bouten CV

In-vitro engineered human cerebral tissues mimic pathological circuit disturbances in 3D

Commun Biol , 2022 Mar 23; 5:254. Epub 2022 Mar 23

PubMed ID: 35322168 DOI: 10.1038/s42003-022-03203-4

Mora-Jimenez L, Valencia M, Sanchez-Carpintero R, Tønnesen J, Fadila S, Rubinstein M, Gonzalez-Aparicio M, Bunuales M, Fernandez-Pierola E, Nicolas MJ, Puerta E, Miguelez C, Minguez PG, Lumbreras S, Gonzalez-Aseguinolaza G, Ricobaraza A, Hernandez-Alcoceba R

Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations

Mol Ther Nucleic Acids , 2021 Aug 19; 25:585-602. Epub 2021 Aug 19

PubMed ID: 34589280 DOI: 10.1016/j.omtn.2021.08.003

Lee W, Lavery L, Rousseaux MW, Rutledge EB, Jang Y, Wan Y, Wu S, Kim W, Al‐Ramahi I, Rath S, Adamski CJ, Bondar VV, Tewari A, Soleimani S, Mota S, Yalamanchili HK, Orr HT, Liu Z, Botas J, Zoghbi HY

Dual targeting of brain region‐specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1

EMBO J , 2021 Mar 11; 40(7):e106106. Epub 2021 Mar 11

PubMed ID: 33709453 DOI: 10.15252/embj.2020106106

Tristan CA, Ormanoglu P, Slamecka J, Malley C, Chu PH, Jovanovic VM, Gedik Y, Bonney C, Barnaeva E, Braisted J, Mallanna SK, Dorjsuren D, Iannotti MJ, Voss TC, Michael S, Simeonov A, Singeç I

Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells

bioRxiv , . Epub 2020 Aug 3

PubMed ID: 32793899 DOI: 10.1101/2020.08.03.235242

Vázquez-Vélez GE, Gonzales KA, Revelli JP, Adamski CJ, Alavi Naini F, Bajić A, Craigen E, Richman R, Heman-Ackah SM, Wood MJ, Rousseaux MW, Zoghbi HY

Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity

J Neurosci , 2020 Jan 8; 40(2):459-477

PubMed ID: 31748376 DOI: 10.1523/JNEUROSCI.1076-19.2019

Larsson M, Broman J

Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord

eNeuro , 2019 Feb 14; 6(1):ENEURO.0007-19.2019. Epub 2019 Feb 14

PubMed ID: 30783617 DOI: 10.1523/ENEURO.0007-19.2019

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Alternative Antibodies
Anti-SLC17A7 (HPA050458)
Anti-VGLUT1 (HPA063679)
Corresponding Antigens
PrEST Antigen VGLUT1 (APrEST88047)

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