Monoclonal Anti-RBM3 Antibody
Human Protein Atlas
Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000005387 (96%)
Mouse ENSMUSG00000031167 (94%)
Dilution: 1:500 - 1:1000
Retrieval method: HIER pH6
Working concentration: 1 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 2-10 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Genetic validation in WB by siRNA knockdown.
Pre-clinical and clinical studies on the role of RBM3 in muscle-invasive bladder cancer: longitudinal expression, transcriptome-level effects and modulation of chemosensitivity
BMC Cancer , 2022 Feb 2; 22:131. Epub 2022 Feb 2
Delineating the intra-patient heterogeneity of molecular alterations in treatment-naïve colorectal cancer with peritoneal carcinomatosis
Mod Pathol , 2022 Feb 15; 35(7):979-988. Epub 2022 Feb 15
Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non‐small cell lung cancer
Cancer Med , 2020 Jun 3; 9(15):5609-5619. Epub 2020 Jun 3
Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification
Oncotarget , 2017 Dec 15; 9(5):6188-6200. Epub 2017 Dec 15
Podocalyxin-like and RNA-binding motif protein 3 are prognostic biomarkers in urothelial bladder cancer: a validatory study
Biomark Res , 2017 Mar 14; 5:10. Epub 2017 Mar 14
Evaluation of RNA-binding motif protein 3 expression in urothelial carcinoma of the bladder: an immunohistochemical study.
World J Surg Oncol , 2015 Nov 14; 13(None):317
Low RBM3 Protein Expression Correlates with Clinical Stage, Prognostic Classification and Increased Risk of Treatment Failure in Testicular Non-Seminomatous Germ Cell Cancer.
PLoS One , 2015; 10(3):e0121300
Evaluating real-time immunohistochemistry on multiple tissue samples, multiple targets and multiple antibody labeling methods
BMC Res Notes , 2013 Dec 18; 6:542. Epub 2013 Dec 18
Decreased expression of RNA-binding motif protein 3 correlates with tumour progression and poor prognosis in urothelial bladder cancer.
BMC Urol , 2013 Apr 8; 13(None):17
High MCM3 expression is an independent biomarker of poor prognosis and correlates with reduced RBM3 expression in a prospective cohort of malignant melanoma
Diagn Pathol , 2012 Jul 17; 7:82. Epub 2012 Jul 17
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer.
Proteomics Clin Appl , 2011 Dec; 5(11-12):624-35
High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.
Diagn Pathol , 2011 Sep 28; 6:91. Epub 2011 Sep 28
RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer.
Transl Oncol , 2011 Aug; 4(4):212-21. Epub 2011 Aug 1
Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: an analysis of 215 cases from the Malmö Diet and Cancer Study.
J Transl Med , 2011 Jul 21; 9:114. Epub 2011 Jul 21
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.
J Transl Med , 2010 Aug 20; 8:78. Epub 2010 Aug 20
Join the Explorer Program
Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.