Human Protein Atlas
Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000005387 (96%)
Mouse ENSMUSG00000031167 (94%)
Dilution: 1:500 - 1:1000
Retrieval method: HIER pH6
Working concentration: 1 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 2-10 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Genetic validation in WB by siRNA knockdown.
Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification
Oncotarget , 2017 Dec 15; 9(5):6188-6200. Epub 2017 Dec 15
Podocalyxin-like and RNA-binding motif protein 3 are prognostic biomarkers in urothelial bladder cancer: a validatory study
Biomark Res , 2017 Mar 14; 5:10. Epub 2017 Mar 14
Evaluation of RNA-binding motif protein 3 expression in urothelial carcinoma of the bladder: an immunohistochemical study.
World J Surg Oncol , 2015 Nov 14; 13(None):317
Low RBM3 Protein Expression Correlates with Clinical Stage, Prognostic Classification and Increased Risk of Treatment Failure in Testicular Non-Seminomatous Germ Cell Cancer.
PLoS One , 2015; 10(3):e0121300
Evaluating real-time immunohistochemistry on multiple tissue samples, multiple targets and multiple antibody labeling methods
BMC Res Notes , 2013 Dec 18; 6:542. Epub 2013 Dec 18
Decreased expression of RNA-binding motif protein 3 correlates with tumour progression and poor prognosis in urothelial bladder cancer.
BMC Urol , 2013 Apr 8; 13(None):17
High MCM3 expression is an independent biomarker of poor prognosis and correlates with reduced RBM3 expression in a prospective cohort of malignant melanoma
Diagn Pathol , 2012 Jul 17; 7:82. Epub 2012 Jul 17
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer.
Proteomics Clin Appl , 2011 Dec; 5(11-12):624-35
High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.
Diagn Pathol , 2011 Sep 28; 6:91. Epub 2011 Sep 28
RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer.
Transl Oncol , 2011 Aug; 4(4):212-21. Epub 2011 Aug 1
Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: an analysis of 215 cases from the Malmö Diet and Cancer Study.
J Transl Med , 2011 Jul 21; 9:114. Epub 2011 Jul 21
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.
J Transl Med , 2010 Aug 20; 8:78. Epub 2010 Aug 20
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