Monoclonal Anti-HMGCR Antibody


Human Protein Atlas
Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000021670 (94%)
Rat ENSRNOG00000016122 (92%)
Recommended conditions:
Dilution: 1:20 - 1:50
Retrieval method: HIER pH6
Recommended conditions:
Working concentration: 1 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Genetic validation in WB by siRNA knockdown.
High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer
Oncotarget , 2016 Jul 21; 7(37):59640-59651. Epub 2016 Jul 21
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