Enhanced Validation

Monoclonal Anti-HMGCR Antibody

3-hydroxy-3-methylglutaryl-coa reductase
Recommended Applications
Genetic validation in WB by siRNA knockdown.
Product Description
Monoclonal Antibody against Human HMGCR
Product Number
Unit Size
Lot dependent
>10 in Stock
Ready to Ship
Target Protein
3-hydroxy-3-methylglutaryl-coa reductase
Target Gene
Verified Species Reactivity
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000021670 (96%)

Rat ENSRNOG00000016122 (96%)

Clone ID
The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Protein A purified
The antibody solution should be gently mixed before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:50 - 1:200

Retrieval method: HIER pH6

Western Blot (WB)

Recommended conditions:

Working concentration: 1 µg/ml

Western Blot (WB)

Genetic validation in WB by siRNA knockdown.

Protein Name
3-hydroxy-3-methylglutaryl-coa reductase
Gene Name
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Normally shipped at ambient temperature
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Ranea-Robles P, Chen H, Stauffer B, Yu C, Bhattacharya D, Friedman SL, Puchowicz M, Houten SM

The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis

J Inherit Metab Dis , 2021 Oct 2; 44(6):1419-1433. Epub 2021 Oct 2

PubMed ID: 34564857 DOI: 10.1002/jimd.12440

Warita K, Ishikawa T, Sugiura A, Tashiro J, Shimakura H, Hosaka YZ, Ohta KI, Warita T, Oltvai ZN

Concomitant attenuation of HMGCR expression and activity enhances the growth inhibitory effect of atorvastatin on TGF-β-treated epithelial cancer cells

Sci Rep , 2021 Jun 17; 11:12763. Epub 2021 Jun 17

PubMed ID: 34140545 DOI: 10.1038/s41598-021-91928-3

Bjarnadottir O, Feldt M, Inasu M, Bendahl PO, Elebro K, Kimbung S, Borgquist S

Statin use, HMGCR expression, and breast cancer survival – The Malmö Diet and Cancer Study

Sci Rep , 2020 Jan 17; 10:558. Epub 2020 Jan 17

PubMed ID: 31953433 DOI: 10.1038/s41598-019-57323-9

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Join the Explorer Program

Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.

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