Monoclonal Anti-HMGCR Antibody
Human Protein Atlas
Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000021670 (96%)
Rat ENSRNOG00000016122 (96%)
Dilution: 1:20 - 1:50
Retrieval method: HIER pH6
Working concentration: 1 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Genetic validation in WB by siRNA knockdown.
The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis
J Inherit Metab Dis , 2021 Oct 2; 44(6):1419-1433. Epub 2021 Oct 2
Concomitant attenuation of HMGCR expression and activity enhances the growth inhibitory effect of atorvastatin on TGF-β-treated epithelial cancer cells
Sci Rep , 2021 Jun 17; 11:12763. Epub 2021 Jun 17
Statin use, HMGCR expression, and breast cancer survival – The Malmö Diet and Cancer Study
Sci Rep , 2020 Jan 17; 10:558. Epub 2020 Jan 17
Join the Explorer Program
Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.