Enhanced Validation

Monoclonal Anti-FUS Antibody

fused in sarcoma
Recommended Applications
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Genetic validation in WB by siRNA knockdown.
Product Description
Monoclonal Antibody against Human FUS
Alternative Gene Names
Product Number
Unit Size
Lot dependent
>10 in Stock
Ready to Ship
Target Protein
fused in sarcoma
Target Gene
Belongs to Antibody Panel
Verified Species Reactivity
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000030795 (91%)

Rat ENSRNOG00000023360 (91%)

Clone ID
40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Protein A purified
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:2500 - 1:5000

Retrieval method: HIER pH6

Western Blot (WB)

Recommended conditions:

Working concentration: 1 µg/ml

Immunofluorescence in Cell Lines (ICC-IF)

Recommended conditions:

Fixation/Permeabilization: PFA/Triton X-100

Working concentration: 2-10 µg/ml

Immunohistochemistry (IHC)

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

Western Blot (WB)

Genetic validation in WB by siRNA knockdown.

Protein Name
fused in sarcoma
Gene Name
Alternative Gene Names
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Normally shipped at ambient temperature
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Castillo Bautista CM, Eismann K, Gentzel M, Pelucchi S, Mertens J, Walters HE, Yun MH, Sterneckert J

Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy

Cells , 2023 Sep 11; 12(18):2247. Epub 2023 Sep 11

PubMed ID: 37759469 DOI: 10.3390/cells12182247

Rosario R, Stewart HL, Choudhury NR, Michlewski G, Charlet‐Berguerand N, Anderson RA

Evidence for a fragile X messenger ribonucleoprotein 1 (FMR1) mRNA gain‐of‐function toxicity mechanism contributing to the pathogenesis of fragile X‐associated premature ovarian insufficiency

FASEB J , 2022 Oct 17; 36(11):e22612. Epub 2022 Oct 17

PubMed ID: 36250920 DOI: 10.1096/fj.202200468RR

Raykova D, Kermpatsou D, Malmqvist T, Harrison PJ, Sander MR, Stiller C, Heldin J, Leino M, Ricardo S, Klemm A, David L, Spjuth O, Vemuri K, Dimberg A, Sundqvist A, Norlin M, Klaesson A, Kampf C, Söderberg O

A method for Boolean analysis of protein interactions at a molecular level

Nat Commun , 2022 Aug 13; 13:4755. Epub 2022 Aug 13

PubMed ID: 35963857 DOI: 10.1038/s41467-022-32395-w

Decker CJ, Burke JM, Mulvaney PK, Parker R

RNA is required for the integrity of multiple nuclear and cytoplasmic membrane‐less RNP granules

EMBO J , 2022 Mar 31; 41(9):e110137. Epub 2022 Mar 31

PubMed ID: 35355287 DOI: 10.15252/embj.2021110137

Marrone L, Drexler HC, Wang J, Tripathi P, Distler T, Heisterkamp P, Anderson EN, Kour S, Moraiti A, Maharana S, Bhatnagar R, Belgard TG, Tripathy V, Kalmbach N, Hosseinzadeh Z, Crippa V, Abo-Rady M, Wegner F, Poletti A, Troost D, Aronica E, Busskamp V, Weis J, Pandey UB, Hyman AA, Alberti S, Goswami A, Sterneckert J

FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

Acta Neuropathol , 2019 Apr 1; 138(1):67-84. Epub 2019 Apr 1

PubMed ID: 30937520 DOI: 10.1007/s00401-019-01998-x

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Alternative Antibodies
Corresponding Antigens


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