Monoclonal Anti-FUS Antibody
Human Protein Atlas
Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000030795 (91%)
Rat ENSRNOG00000023360 (91%)
Dilution: 1:2500 - 1:5000
Retrieval method: HIER pH6
Working concentration: 1 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 2-10 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Genetic validation in WB by siRNA knockdown.
Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy
Cells , 2023 Sep 11; 12(18):2247. Epub 2023 Sep 11
Evidence for a fragile X messenger ribonucleoprotein 1 (FMR1) mRNA gain‐of‐function toxicity mechanism contributing to the pathogenesis of fragile X‐associated premature ovarian insufficiency
FASEB J , 2022 Oct 17; 36(11):e22612. Epub 2022 Oct 17
A method for Boolean analysis of protein interactions at a molecular level
Nat Commun , 2022 Aug 13; 13:4755. Epub 2022 Aug 13
RNA is required for the integrity of multiple nuclear and cytoplasmic membrane‐less RNP granules
EMBO J , 2022 Mar 31; 41(9):e110137. Epub 2022 Mar 31
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy
Acta Neuropathol , 2019 Apr 1; 138(1):67-84. Epub 2019 Apr 1
Join the Explorer Program
Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.