Monoclonal Anti-CNP Antibody
Lane 2: Human Cerebral Cortex tissue
Human Protein Atlas
Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000017496 (77%)
Mouse ENSMUSG00000006782 (76%)
Dilution: 1:10000 - 1:20000
Retrieval method: HIER pH6
Working concentration: 1 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 2-10 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Validated in Western blot using relevant lysates (see Western blot application images above)
Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development
Cereb Cortex , 2022 Dec 27; 33(10):5906-5923. Epub 2022 Dec 27
Microglia regulate central nervous system myelin growth and integrity
Nature , 2022 Dec 14; 613(7942):120-129. Epub 2022 Dec 14
Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis
Metabolites , 2022 Jun 17; 12(6):554. Epub 2022 Jun 17
New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination
Nat Neurosci , 2022 Feb 14; 25(4):415-420. Epub 2022 Feb 14
Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model
Brain Commun , 2021 Oct 26; 3(4):fcab255. Epub 2021 Oct 26
Oligodendrocyte HCN2 Channels Regulate Myelin Sheath Length
J Neurosci , 2021 Sep 22; 41(38):7954-7964
iPSC-derived myelinoids to study myelin biology of humans
Dev Cell , 2021 May 3; 56(9):1346-1358.e6
Staining and Quantitative Analysis of Myelinating Oligodendrocytes in the Mouse Grey Matter
Bio Protoc , 2020 Oct 20; 10(20):e3792. Epub 2020 Oct 20
Endothelin signalling mediates experience-dependent myelination in the CNS
eLife , 2019 Oct 28; 8:e49493. Epub 2019 Oct 28
Scaffold-Mediated Sustained, Non-viral Delivery of miR-219/miR-338 Promotes CNS Remyelination
Mol Ther , 2018 Dec 1; 27(2):411-423. Epub 2018 Dec 1
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