Research Highlights:
Protein Markers in Glioma Research
Author: Laura Pozzi Ph.D., Scientific Content Manager, Atlas Antibodies AB, Sweden
Recent studies in glioma research have revealed the critical importance of new biomarkers to revolutionize the diagnosis, prognosis, and treatment of this aggressive brain tumor. By leveraging protein markers, researchers can gain greater insight into the underlying mechanisms of gliomas and develop more effective therapeutic strategies.
Gliomas are a type of brain tumor that arises from the glial cells, which provide support and nourishment to the neurons. They are known to be highly invasive and aggressive, making them one of the most challenging types of brain tumors to treat. Protein markers play a crucial role in understanding the underlying mechanisms of these tumors and developing effective treatment strategies. Read on to discover how our antibodies are used in glioma research.
Traditionally, glioma diagnosis relied on imaging techniques such as magnetic resonance imaging (MRI) and histopathological analysis. While these methods are extremely valuable, they have limitations in terms of sensitivity and specificity. Protein markers offer the potential for more precise and reliable diagnostic approaches, leading to early detection and ultimately improved patient outcomes.
Understanding Glioma Biomarkers
Biomarkers are measurable substances or indicators that can be found in the body and are associated with a particular condition or disease. In the context of glioma research, biomarkers serve as crucial tools for early detection, accurate diagnosis, and monitoring treatment response. They provide valuable information about the genetic, molecular, and metabolic alterations associated with gliomas.
In gliomas neuropathological diagnostics, antibodies directed towards proteins such as IDH (isocitrate dehydrogenase), ATRX (alpha thalassemia/mental retardation syndrome X-linked), GFAP (glial fibrillary acidic protein), SYN (synaptophysin), EGFR (epidermal growth factor receptor), p53 (tumor suppressor protein 53), and the proliferation marker Ki-67 (MKI67) are the gold standard and routinely used for gliomas classification.