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Glioma Markers

Gliomas are one of the most aggressive and lethal solid tumors of the central nervous system. Despite the alarming numbers, the molecular pathogenetic mechanisms of gliomas are not yet fully elucidated. Nowadays, several approaches aim to understand the biology of the disease and identify promising markers, which may provide effective novel therapies.

Brain tumors comprise approximately 2% of all adult cancers but form a larger fraction within the group of childhood tumors. Gliomas account for about 80% of all malignant brain tumors and are classified according to the cell type of origin, differentiation, and malignancy grade. Gliomas show considerable variability in age of onset, grade of severity, histological features, and ability to progress, as well as to metastasize

 

Anti-PTEN Antibody
Anti-PTEN Antibody

Anti-PTEN Antibody

AMAb91736
In Stock (10+)
3 490 kr
Anti-EZH2 Antibody
Anti-EZH2 Antibody

Anti-EZH2 Antibody

AMAb91749
In Stock (10+)
3 490 kr
Anti-ID1 Antibody
Anti-ID1 Antibody

Anti-ID1 Antibody

AMAb91757
In Stock (10+)
4 106 kr
Anti-CHI3L1 Antibody
Anti-CHI3L1 Antibody

Anti-CHI3L1 Antibody

AMAb91778
In Stock (10+)
4 106 kr
Anti-SALL4 Antibody

Anti-SALL4 Antibody

AMAb91770
In Stock (10+)
4 106 kr
Anti-FOXO3 Antibody
Anti-FOXO3 Antibody

Anti-FOXO3 Antibody

AMAb91872
In Stock (10+)
3 490 kr
Anti-LGR5 Antibody
Anti-LGR5 Antibody

Anti-LGR5 Antibody

AMAb91887
In Stock (10+)
4 106 kr
Anti-ADAM10 Antibody
Anti-ADAM10 Antibody

Anti-ADAM10 Antibody

AMAb91901
In Stock (10+)
4 106 kr
Anti-TSPAN13 Antibody
Anti-TSPAN13 Antibody

Anti-TSPAN13 Antibody

HPA007426
In Stock (10+)
4 352 kr
Anti-TBL1XR1 Antibody
Anti-TBL1XR1 Antibody

Anti-TBL1XR1 Antibody

HPA019182
In Stock (10+)
4 352 kr
Anti-STC1 Antibody
Anti-STC1 Antibody

Anti-STC1 Antibody

HPA023918
In Stock (10+)
4 106 kr
Anti-ZNF821 Antibody
Anti-ZNF821 Antibody

Anti-ZNF821 Antibody

HPA036372
In Stock (10+)
4 352 kr

 
Download the Glioma Markers white paper

The white paper summarizes the recent developments in glioma classification and the key molecular markers for glioma stratification. Next, it highlights the glioma proteome with a list of relevant genes with favorable and unfavorable prognostic values in glioma. It then focuses on the glioma tumor microenvironment that may provide helpful insights when developing novel therapeutic strategies.

Learning points:

  • The most common form of glioma - astrocytoma
  • Glioma classification and key molecular pathology
  • Adult and pediatric gliomas: distinctive features
  • The glioma proteome
  • The glioma tumor microenvironment
  • Immunomodulation
  • Angiogenesis
  • Glioma cancer stem cells and drug resistance
  • Chi3l1 as a modulator of stem cells' cellular states
  • References
Glioma Markers