Cancer Stem Cell Markers
Cancer stem cells (CSCs) are small cells, 1% to 3% of all cells in a tumor, that drive the tumor’s initiation, growth, and metastasis and may cause relapse. Due to their importance, several biomarkers that characterize CSCs have been identified, allowing diagnostic, therapeutic, and prognostic predictions.
Thus, selectively targeting CSCs with specific antibodies holds hope for improving cancer patients’ survival and is a promising therapeutic strategy against cancer.
Here we provide an overview of the most prominent CSC markers, focusing on solid cancers (lung, stomach, liver, breast, and colorectal cancers) and hematological cancers (acute and chronic myeloid leukemia).