Human Protein Atlas

The Human Protein Atlas is a unique world-leading effort to map all the human proteins in cells, tissues, and organs in the human body using antibody-based imaging, mass spectrometry-based proteomics, transcriptomics, and systems biology. 

Mapping human protein expression

The Human Protein Atlas project was initiated in 2003 by Swedish researchers, headed by Professor Mathias Uhlén, and funded by the Knut and Alice Wallenberg foundation. It is a unique world-leading effort, performing systematic exploration of the human proteome. The project has created an expression map of the complete human proteome. The result is an open-access database, where scientists can explore human protein expression.  

The Human Protein Atlas database is divided into six parts, the Tissue Atlas, Cell Atlas, Pathology Atlas, Brain Atlas, Blood Atlas, and Metabolic Atlas. Each section focuses on a particular aspect of analysis of the human proteins.

As part of creating the human protein expression map, highly specific premium antibodies were developed to all protein-coding human genes, and protein profiling established in a multitude of tissues and cells. These antibodies are manufactured and made available to fellow researchers by Atlas Antibodies as Triple A Polyclonals .

 

Atlas Antibodies and the Human Protein Atlas

Atlas Antibodies was founded in 2006 to commercialize the antibodies developed within the Human Protein Atlas project. All Triple A Polyclonals are carefully designed and manufactured to achieve the very highest level of specificity, reproducibility, and versatility. For every antibody, you have free access to over 500 IHC images from all major human organs and all major cancer types on the Human Protein Atlas. 

Discover Triple A Polyclonals

The Tissue Atlas

The Tissue Atlas section of the Human Protein Atlas is a map of the human tissue proteome. It contains information on the expression profiles of human genes at the mRNA and protein level. Explore IHC stainings from 44 normal human tissues using our Triple A Polyclonals. 

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The Cell Atlas

The Cell Atlas section of the Human Protein Atlas is a map of the subcellular proteome. It provides high-resolution insights into the spatiotemporal distribution of proteins within human cells. It an amazing resource for exploring details of individual genes and proteins.

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The Brain Atlas

The Brain Atlas section of the Human Protein Atlas explores protein expression in the brain by integrating human, pig and mouse data. Explore IHC stainings from ten human brain regions and stainings on consecutive sections of the entire mouse brain using our Triple A Polyclonals.

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The Pathology Atlas

The Pathology Atlas section of the Human Protein Atlas provides information on the role of genes, RNA, proteins, and metabolites in human cancerous tissues and organs. It is a valuable resource for cancer research.

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The Blood Atlas

The Blood Atlas section of the Human Protein Atlas is an open-access database focusing on the expression levels of all human protein-coding genes in major blood immune cell populations, as well as proteins actively secreted to blood.  

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Guides

Interested in using the Human Protein Atlas but not sure where to start? Discover our user guides. 

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Posters

Human Proteome Poster

Human Proteome Poster

Get our free poster to discover how the Human Protein Atlas have mapped the human tissue proteome using Triple A Polyclonals. 

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Human Cell Poster

Human Cell Poster

Interested in the human cell? Order a free copy of this full size poster to learn about the most detailed mapping of the human cell ever done.

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Human Brain Poster

Human Brain Poster

Interested in neuroscience and the human brain? Order a free copy of this poster to explore the Brain Atlas, a subsection of the Human Protein Atlas.

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Human Blood Poster

Human Blood Poster

Interested in human blood proteins and the secretome? Order a free copy of this poster to learn about the Blood Atlas, a subsection of the Human Protein Atlas

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Dictionaries for learning about histology and cell structure

The Dictionaries are useful tools available at The Human Protein Atlas. Their purpose is not only to facilitate the interpretation and use of data available in the Human Protein Atlas but also to serve as tools for learning and understanding human tissue histology, pathology, and cell biology. The dictionary contains four parts, the Normal Tissue Histology, Cancer Histology, Cell Structure, and Protein Expression.

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Webinars

Learn more about the Human Protein Atlas and the research behind the atlas in our webinar series. 

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