The Human Protein Atlas
The Human Protein Atlas is a unique world-leading effort to map all the human proteins in cells, tissues, and organs in the human body using antibody-based imaging, mass spectrometry-based proteomics, transcriptomics, and systems biology.
Atlas Antibodies and the Human Protein Atlas
Atlas Antibodies was founded in 2006 by researchers from the Human Protein Atlas.
As part of creating the human protein expression map, researchers from the Human Protein Atlas project developed highly specific polyclonal antibodies targeting all protein-coding human genes.
Atlas Antibodies manufacture and commercialize these polyclonal antibodies as Triple A Polyclonals.
All Triple A Polyclonals are carefully designed and manufactured to achieve the very highest level of specificity, reproducibility, and versatility. For each antibody, you have free access to over 500 IHC staining images of all major human organs and cancer types.
New Triple A Polyclonals - Human Protein Atlas release 2023
The Human Protein Atlas releases a new version of its resource each year with expanded data.
Triple A Polyclonals for tissue and cell analysis.
The products listed in the brochure are a selection of TripleA Polyclonals released this year.
Additionally, polyclonal antibodies offer robustness and versatility, allowing you to explore the heterogeneity of tissues, organs, and cells, leading to a deeper understanding of human biology and the development of targeted therapies for different diseases.
👉 Here you can find the full list of Triple A Polyclonals released in HPA version 23.
12 ways to explore the human proteome
The Tissue Atlas
The tissue-based map of the human proteome
Expression profiles of human genes at the mRNA and protein levels. Explore immunohistochemical stainings from 44 human tissues using our Triple A Polyclonals.
The Subcellular Atlas
The map of the human proteome at subcellular level
High-resolution insights into the distribution of the proteins within 35 organelles and fine subcellular structures of the human cells using our Triple A Polyclonals.
The Brain Atlas
The protein profiles of the mammalian brain
Comprehensive spatial protein profiling of the mammalian brains - human, pigs, and mice - using our Triple A Polyclonals.
The Pathology Atlas
The protein expression profiles of human cancers
The Pathology Atlas provides information on the role of genes, mRNA, and protein expression from 17 forms of human cancer and tissue using our Triple A Polyclonals.
The Blood Protein Atlas
The proteins in the human blood
Estimated plasma concentrations of proteins in the human blood and proteins actively secreted to blood using our Triple A Polyclonals.
The Cell Line Atlas
The protein expression profiles in human cell lines
The Cell Line section contains information on genome-wide RNA expression profiles of human protein-coding genes in 69 human cell lines.
The Single Cell Type Atlas
The protein expression profiles in single-cell types
Information based on single-cell RNA sequencing data from 25 human tissues and peripheral blood mononuclear cells, together with IHC tissue staining visualizing the spatial profile of the corresponding protein.
The Tissue Cell Type Atlas
The cell-type specificity of genes within human tissues
Cell type expression specificity predictions for all human protein-coding genes, to learn which genes have predicted enriched expression in cell types, across multiple human tissues.
The Immune Cell Atlas
The protein expression profile in human immune cells
Expression profiles of human protein-coding genes in B- and T-cells, monocytes, granulocytes, and dendritic cells to learn which genes are enriched in a particular immune cell type or have a similar expression profile across the immune cells.
The Metabolic Atlas
The expression profiles of enzymes involved in human metabolism
Tissue-specific gene expression and exploration of protein functions in the human metabolic network. Over 120 metabolic pathway maps facilitate the visualization of each protein's participation in different metabolic processes.
The Human Disease Blood Atlas
The disease section
The Human Disease Blood Atlas contains information on protein levels in blood in patients with different diseases and highlights proteins associated with these diseases Protein profiles have been quantified across 12 major cancer types.
The 3D structure section
The three-dimensional structure of human proteins.
The predicted 3D structure from the AlphaFold Protein Structure Database project is shown together with experimentally determined structures from the Protein Data Bank. All antigens with known sequences have been mapped and can be displayed on the protein structures.
The Human Protein Atlas Dictionary
The purpose of the dictionary is to facilitate the interpretation and use of the image-based data available in the Human Protein Atlas, but also to serve as a tool for training and understanding histology, pathology, and cell biology. The dictionary contains three main parts: normal tissue histology, pathology, and cell structure.
The aim of this section is to educate readers about the histology of normal and cancer tissues, which provides important and basic information for our understanding of biology and medicine. The dictionary covering cell structure is built around antibody-based stainings of proteins in cell lines using immunofluorescence and confocal microscopy.
Webinars
Learn more about the Human Protein Atlas and the research behind the atlas in our webinar series.