Polyclonal Anti-YTHDC2 Antibody

YTH domain containing 2
Recommended Applications
Product Description
Polyclonal Antibody against Human YTHDC2
Alternative Gene Names
DKFZp564A186, FLJ10053, FLJ2194
Product Number
Unit Size
Lot dependent
>10 in Stock
Ready to Ship
Target Protein
YTH domain containing 2
Target Gene
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
Verified Species Reactivity
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Rat ENSRNOG00000039241 (97%)

Mouse ENSMUSG00000034653 (94%)

40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:1000 - 1:2500

Retrieval method: HIER pH6

Protein Name
YTH domain containing 2
Gene Name
Alternative Gene Names
DKFZp564A186, FLJ10053, FLJ2194
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Normally shipped at ambient temperature
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000047188 on the Human Protein Atlas

McGlacken-Byrne SM, Del Valle I, Quesne Stabej PL, Bellutti L, Garcia-Alonso L, Ocaka LA, Ishida M, Suntharalingham JP, Gagunashvili A, Ogunbiyi OK, Mistry T, Buonocore F, GOSgene, Crespo B, Moreno N, Niola P, Brooks T, Brain CE, Dattani MT, Kelberman D, Vento-Tormo R, Lagos CF, Livera G, Conway GS, Achermann JC

Pathogenic variants in the human m6A reader YTHDC2 are associated with primary ovarian insufficiency

JCI Insight , 2022 Mar 8; 7(5):e154671. Epub 2022 Mar 8

PubMed ID: 35138268 DOI: 10.1172/jci.insight.154671

He JJ, Li Z, Rong ZX, Gao J, Mu Y, Guan YD, Ren XX, Zi YY, Liu LY, Fan Q, Zhou M, Duan YM, Zhou Q, Deng YZ, Sun LQ

m6A Reader YTHDC2 Promotes Radiotherapy Resistance of Nasopharyngeal Carcinoma via Activating IGF1R/AKT/S6 Signaling Axis

Front Oncol , 2020 Jul 31; 10:1166. Epub 2020 Jul 31

PubMed ID: 32850334 DOI: 10.3389/fonc.2020.01166

Kretschmer J, Rao H, Hackert P, Sloan KE, Höbartner C, Bohnsack MT

The m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5′–3′ exoribonuclease XRN1

RNA , 2018 Oct; 24(10):1339-1350

PubMed ID: 29970596 DOI: 10.1261/rna.064238.117

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Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.

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Alternative Antibodies
Corresponding Antigens


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