Polyclonal Anti-USP46 Antibody

ubiquitin specific peptidase 46
References (3)
Recommended Applications
Product Description
Polyclonal Antibody against Human USP46
Alternative Gene Names
FLJ12552
Open Datasheet
Price
$505.00
Product Number
HPA007288
Unit Size
Concentration
Lot dependent
Availability
>10 in Stock
Ships
Ready to Ship
Show all images
[4 pictures]
Immunohistochemical staining of human Cerebral cortex shows moderate cytoplasmic positivity in neuronal cells.

Additional Images

See additional IHC images using this antibody for 44 normal tissues and 20 cancers on the Human Protein Atlas
Target Protein
ubiquitin specific peptidase 46
Target Gene
USP46
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
LFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQN
Verified Species Reactivity
Human
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000054814 (100%)

Rat ENSRNOG00000002106 (99%)

Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Buffer
40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Concentration
Product Data Sheet
Download data sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:200 - 1:500

Retrieval method: HIER pH6

Protocols
View all protocols
Protein Name
ubiquitin specific peptidase 46
Gene Name
USP46
Alternative Gene Names
FLJ12552
UniProt ID
P62068
Gene (Ensembl)
ENSG00000109189
Entrez Gene ID
Entrez gene: 64854
Shipping
Normally shipped at ambient temperature
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000109189 on the Human Protein Atlas

Kiran S, Dar A, Singh SK, Lee KY, Dutta A

The deubiquitinase USP46 is essential for proliferation and tumor growth of HPV-transformed cancers

Mol Cell , 2018 Nov 8; 72(5):823-835.e5. Epub 2018 Nov 8

PubMed ID: 30415951 DOI: 10.1016/j.molcel.2018.09.019

Ohashi M, Holthaus AM, Calderwood MA, Lai CY, Krastins B, Sarracino D, Johannsen E

The EBNA3 Family of Epstein-Barr Virus Nuclear Proteins Associates with the USP46/USP12 Deubiquitination Complexes to Regulate Lymphoblastoid Cell Line Growth

PLoS Pathog , 2015 Apr; 11(4):e1004822. Epub 2015 Apr 9

PubMed ID: 25855980 DOI: 10.1371/journal.ppat.1004822

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Join the Explorer Program

Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.

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Alternative Antibodies
Anti-USP46 (AMAb90722)
Anti-USP46 (AMAb90723)
Corresponding Antigens
PrEST Antigen USP46 (APrEST70798)

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