Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000029223 (97%)
Rat ENSRNOG00000002343 (97%)
Dilution: 1:2500 - 1:5000
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Axon-like protrusions promote small cell lung cancer migration and metastasis
eLife , 2019 Dec 13; 8:e50616. Epub 2019 Dec 13
Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells
mBio , 2019 Jul 16; 10(4):e01372-19. Epub 2019 Jul 16
Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition
Cancer Discov , 2018 Sep 4; 8(11):1422-1437. Epub 2018 Sep 4
Inter-tumoral heterogeneity in SCLC is influenced by the cell-type of origin
Cancer Discov , 2018 Sep 18; 8(10):1316-1331. Epub 2018 Sep 18
Prognostic potential and oncogenic effects of UCH-L1 expression in hilar cholangiocarcinoma
Int J Clin Exp Pathol , 2017 Nov 1; 10(11):10802-10811. Epub 2017 Nov 1
UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization
Sci Rep , 2017 Jul 31; 7:6879. Epub 2017 Jul 31
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
Nature , 545, 360-364 (2017)
Intratumoral heterogeneity generated by Notch signaling promotes small cell lung cancer
Nature , 2017 May 10; 545(7654):360-364. Epub 2017 May 10
The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin
Nature Immunology , November 21, 2016
Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer
Genes Dev , 2016 Jun 1; 30(11):1289-1299
UCH-LI acts as a novel prognostic biomarker in gastric cardiac adenocarcinoma
Int J Clin Exp Pathol , 2015 Nov 1; 8(11):13957-13967. Epub 2015 Nov 1
The prognostic potential and oncogenic effects of PRR11 expression in hilar cholangiocarcinoma
Oncotarget , 2015 Aug 21; 6(24):20419-20433. Epub 2015 May 4
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets.
Discov Med , 2010 Jun; 9(49):565-78
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