Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000005227 (100%)
Mouse ENSMUSG00000005718 (100%)
Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Genetic validation in WB by siRNA knockdown.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Soluble Heparin Binding Epidermal Growth Factor-Like Growth Factor Is a Regulator of GALGT2 Expression and GALGT2-Dependent Muscle and Neuromuscular Phenotypes
Mol Cell Biol , 2019 Jun 27; 39(14):e00140-19. Epub 2019 Jun 27
Modulation of transcription factor binding and epigenetic regulation of the MLH1 CpG island and shore by polymorphism rs1800734 in colorectal cancer
Epigenetics , 2017 Mar 17; 12(6):441-448. Epub 2017 Mar 17
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4
Oncotarget , 2016 Jul 19; 7(34):54937-54951. Epub 2016 Jul 19
AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer
J Exp Med , 2013 Jul 1; 210(7):1331-1350
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