Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000015177 (80%)
Mouse ENSMUSG00000042524 (78%)
Dilution: 1:1000 - 1:2500
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Genetic validation in WB by siRNA knockdown.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading
Nat Commun , 2019 Sep 12; 10:4149. Epub 2019 Sep 12
Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence
PLoS Genet , 2018 Dec 13; 14(12):e1007845. Epub 2018 Dec 13
TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer
Oncotarget , 2016 Nov 24; 7(52):86755-86765. Epub 2016 Nov 24
Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype
PLoS One , 2016 Mar 31; 11(3):e0152321. Epub 2016 Mar 31
SUN2 exerts tumor suppressor functions by suppressing the Warburg effect in lung cancer
Sci Rep , 2015/12/10; 5:17940. Epub 2015 Dec 10
Nuclear envelope-associated endosomes deliver surface proteins to the nucleus
Nat Commun , 2015 Sep 10; 6:8218. Epub 2015 Sep 10
A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton
J Cell Biol , 2013 Sep 30; 202(7):1023-1039
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells.
Nat Methods , 2013 Apr; 10(4):315-23. Epub 2013 Feb 24
BRD4 Short Isoform Interacts with RRP1B, SIPA1 and Components of the LINC Complex at the Inner Face of the Nuclear Membrane
PLoS One , 2013; 8(11):e80746. Epub 2013 Nov 19
Samp1 is functionally associated with the LINC complex and A-type lamina networks.
J Cell Sci , 2011 Jun 15; 124(Pt 12):2077-85
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