Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000057862 (90%)
Mouse ENSMUSG00000024033 (88%)
Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Validation of protein expression in IHC by comparing independent antibodies targeting different epitopes of the protein.
Validated against independent antibody Anti-RSPH1 HPA016816.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Identification of DNAH6 mutations in infertile men with multiple morphological abnormalities of the sperm flagella
Sci Rep , 2019 Nov 1; 9:15864. Epub 2019 Nov 1
Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and Mice
Am J Hum Genet , 2019 Jan 24; 104(2):331-340. Epub 2019 Jan 24
Accuracy of Immunofluorescence in the Diagnosis of Primary Ciliary Dyskinesia
Am J Respir Crit Care Med , 2017 Jul 1; 196(1):94-101. Epub 2017 Jul 1
RSPH3 Mutations Cause Primary Ciliary Dyskinesia with Central-Complex Defects and a Near Absence of Radial Spokes
Am J Hum Genet , 2015/07/02; 97(1):153-162
Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central pair agenesis due to radial spoke defects
Hum Mol Genet , 2014 Jul 1; 23(13):3362-3374. Epub 2014 Feb 11
Loss-of-Function Mutations in RSPH1 Cause Primary Ciliary Dyskinesia with Central-Complex and Radial-Spoke Defects
Am J Hum Genet , 2013 Sep 5; 93(3):561-570
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