Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000054963 (73%)
Mouse ENSMUSG00000026142 (70%)
Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Validated in Western blot using relevant lysates (see Western blot application images above)
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4
J Biol Chem , 2019 Jun 7; 294(30):11486-11497. Epub 2019 Jun 7
Alternative Processing of the Amyloid Precursor Protein Family by Rhomboid Protease RHBDL4
J Biol Chem , 2016 Aug 25; 291(42):21903-21912. Epub 2016 Aug 25
Exosome-Related Multi-Pass Transmembrane Protein TSAP6 Is a Target of Rhomboid Protease RHBDD1-Induced Proteolysis
PLoS One , 2012; 7(5):e37452. Epub 2012 May 18
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