Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000070780 (94%)
Rat ENSRNOG00000002408 (94%)
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Increased expression of the RNA-binding motif protein 47 predicts poor prognosis in non-small-cell lung cancer
Oncol Lett , 2020 Feb 20; 19(4):3111-3122. Epub 2020 Feb 20
RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma
Oncogene , February 29, 2016
Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer
eLife , 2014 Jun 4; 3:e02734. Epub 2014 Jun 4
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