Polyclonal Anti-PDGFRB Antibody

platelet-derived growth factor receptor, beta polypeptide
Recommended Applications
Product Description
Polyclonal Antibody against Human PDGFRB
Alternative Gene Names
CD140b, JTK12, PDGFR, PDGFR1
Price
$505.00
Product Number
HPA028499
Unit Size
Concentration
Lot dependent
Availability
>10 in Stock
Ships
Ready to Ship
Target Protein
platelet-derived growth factor receptor, beta polypeptide
Target Gene
PDGFRB
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
AQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVAL
Verified Species Reactivity
Human
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000024620 (76%)

Rat ENSRNOG00000018461 (76%)

Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Buffer
40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Concentration
Product Data Sheet
Western Blot (WB)

Recommended conditions:

Working concentration: 0.04-0.4 µg/ml

Immunofluorescence in Cell Lines (ICC-IF)

Recommended conditions:

Fixation/Permeabilization: PFA/Triton X-100

Working concentration: 0.25-2 µg/ml

Protocols
Western Blot (WB)

Validated in Western blot using relevant lysates (see Western blot application images above)

Protein Name
platelet-derived growth factor receptor, beta polypeptide
Gene Name
PDGFRB
Alternative Gene Names
CD140b, JTK12, PDGFR, PDGFR1
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Shipping
Normally shipped at ambient temperature
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000113721 on the Human Protein Atlas

Higuchi A, Oshima T, Yoshihara K, Sakamaki K, Aoyama T, Suganuma N, Yamamoto N, Sato T, Cho H, Shiozawa M, Yoshikawa T, Rino Y, Kunisaki C, Imada T, Masuda M

Clinical significance of platelet-derived growth factor receptor-β gene expression in stage II/III gastric cancer with S-1 adjuvant chemotherapy

Oncol Lett , 2016 Dec 14; 13(2):905-911. Epub 2016 Dec 14

PubMed ID: 28356977 DOI: 10.3892/ol.2016.5494

Rorsman C, Tsioumpekou M, Heldin CH, Lennartsson J

The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling

J Biol Chem , 2016 Apr 5; 291(22):11608-11618. Epub 2016 Apr 5

PubMed ID: 27048651 DOI: 10.1074/jbc.M115.705814

Steller EJ, Raats DA, Koster J, Rutten B, Govaert KM, Emmink BL, Snoeren N, van Hooff SR, Holstege FC, Maas C, Borel Rinkes IH, Kranenburg O

PDGFRB Promotes Liver Metastasis Formation of Mesenchymal-Like Colorectal Tumor Cells

Neoplasia , 2013 Feb; 15(2):204-217

PubMed ID: 23441134 DOI: 10.1593/neo.121726

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Join the Explorer Program

Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.

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Corresponding Antigens

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