Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000031173 (93%)
Rat ENSRNOG00000003370 (92%)
Dilution: 1:2500 - 1:5000
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Validation of protein expression in IHC by comparing independent antibodies targeting different epitopes of the protein.
Validated against independent antibody Anti-OTC HPA000570.
Validated in Western blot using relevant lysates (see Western blot application images above)
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes
JHEP Rep , 2019 Dec 27; 2(1):100065. Epub 2019 Dec 27
Adult-Derived Human Liver Stem/Progenitor Cells Infused 3 Days Postsurgery Improve Liver Regeneration in a Mouse Model of Extended Hepatectomy
Cell Transplant , 2017 Feb 1; 26(2):351-364. Epub 2017 Feb 1
Candidate Serological Biomarkers for Cancer Identified from the Secretomes of 23 Cancer Cell Lines and the Human Protein Atlas
Mol Cell Proteomics , 2010 Jun; 9(6):1100-1117. Epub 2010 Feb 1
A Quantitative Proteomic Approach for Identification of Potential Biomarkers in Hepatocellular Carcinoma
J Proteome Res , 2008 Oct; 7(10):4289-4298. Epub 2008 Aug 21
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