Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000014584 (99%)
Mouse ENSMUSG00000026790 (99%)
Dilution: 1:500 - 1:1000
Retrieval method: HIER pH6
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Super-resolution microscopy reveals coupling between mammalian centriole subdistal appendages and distal appendages
eLife , 2020 Apr 3; 9:e53580. Epub 2020 Apr 3
The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome
J Cell Biol , 2017 May 1; 216(5):1287-1300
Spatial control of primary ciliogenesis by subdistal appendages alters sensation-associated properties of cilia
Dev Cell , 2016 Nov 3; 39(4):424-437. Epub 2016 Nov 3
Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 function
Sci Rep , 2016 Apr 20; 6:24083. Epub 2016 Apr 20
Subunit composition of the human cytoplasmic dynein-2 complex
J Cell Sci , 2014 Nov 1; 127(21):4774-4787
A role for the Golgi matrix protein giantin in ciliogenesis through control of the localization of dynein-2
J Cell Sci , 2013 Nov 15; 126(22):5189-5197
Hook2 is involved in the morphogenesis of the primary cilium.
Mol Biol Cell , 2011 Dec; 22(23):4549-62. Epub 2011 Oct 12
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