Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000024431 (72%)
Rat ENSRNOG00000048800 (71%)
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
Recombinant expression validation in WB using target protein overexpression.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Chronic stress and intestinal barrier dysfunction: Glucocorticoid receptor and transcription repressor HES1 regulate tight junction protein Claudin-1 promoter
Sci Rep , 2017 Jul 3; 7:4502. Epub 2017 Jul 3
Glucocorticoids Have Opposing Effects on Liver Fibrosis in Hepatic Stellate and Immune Cells
Mol Endocrinol , 2016 Jun 29; 30(8):905-916. Epub 2016 Jun 29
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