Polyclonal Anti-MTHFD2 Antibody

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
References (2)
Recommended Applications
Product Description
Polyclonal Antibody against Human MTHFD2
Open Datasheet
Price
$505.00
Product Number
HPA049657
Unit Size
Concentration
Lot dependent
Availability
5 in Stock
Ships
Ready to Ship
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[1 pictures]
Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in tubular cells.

Additional Images

See additional IHC images using this antibody for 44 normal tissues and 20 cancers on the Human Protein Atlas
Target Protein
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Target Gene
MTHFD2
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
PASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLL
Verified Species Reactivity
Human
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000005667 (88%)

Rat ENSRNOG00000010833 (85%)

Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Buffer
40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Concentration
Product Data Sheet
Download data sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:50 - 1:200

Retrieval method: HIER pH6

Protocols
View all protocols
Protein Name
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Gene Name
MTHFD2
UniProt ID
P13995
Gene (Ensembl)
ENSG00000065911
Entrez Gene ID
Entrez gene: 10797
Shipping
Normally shipped at ambient temperature
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000065911 on the Human Protein Atlas

Yu C, Yang L, Cai M, Zhou F, Xiao S, Li Y, Wan T, Cheng D, Wang L, Zhao C, Huang X

Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes

J Cell Mol Med , 2019 Nov 28; 24(2):1568-1577. Epub 2019 Nov 28

PubMed ID: 31778025 DOI: 10.1111/jcmm.14844

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Join the Explorer Program

Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.

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Corresponding Antigens
PrEST Antigen MTHFD2 (APrEST78923)

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