Dilution: 1:1000 - 1:2500
Retrieval method: HIER pH6
Working concentration: 0.4 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Validation of protein expression in IHC by comparing independent antibodies targeting different epitopes of the protein.
Validated against independent antibody Anti-MRC1 HPA045134.
Validated in Western blot using relevant lysates (see Western blot application images above)
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Anti–spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection
JCI Insight , 2019 Feb 21; 4(4):e123158. Epub 2019 Feb 21
Clinical and Pathological Findings Associated with Aerosol Exposure of Macaques to Ricin Toxin
Toxins (Basel) , 2015 Jun 9; 7(6):2121-2133. Epub 2015 Jun 9
In vivo characterization of alveolar and interstitial lung macrophages in rhesus macaques: Implications for understanding lung disease in humans
J Immunol , 2014 Mar 15; 192(6):2821-2829. Epub 2014 Feb 17
Renal vein cytokine release as an index of renal parenchymal inflammation in chronic experimental renal artery stenosis
Nephrol Dial Transplant , 2014 Feb; 29(2):274-282. Epub 2013 Oct 3
Mitochondrial targeted peptides attenuate residual myocardial damage after reversal of experimental renovascular hypertension
J Hypertens , 2014 Jan; 32(1):154-165
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