Anti-MED12 Antibody
Validation of protein expression in IHC by comparing independent antibodies targeting different epitopes of the protein.
Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000003848 (94%)
Mouse ENSMUSG00000079487 (94%)
Recommended conditions:
Dilution: 1:20 - 1:50
Retrieval method: HIER pH6
Validation of protein expression in IHC by comparing independent antibodies targeting different epitopes of the protein.
Validated against independent antibody Anti-MED12 HPA003185.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
All characterization data for ENSG00000184634 on the Human Protein Atlas
Cellular kinetics of MED12-mutant uterine leiomyoma growth and regression in vivo
Endocr Relat Cancer , 2018 Apr 26; 25(7):747-759. Epub 2018 Apr 26
Subtype-specific cancer-associated fibroblasts contribute to the pathogenesis of uterine leiomyoma
Cancer Res , 2017 Oct 20; 77(24):6891-6901. Epub 2017 Oct 20
MED12 Alterations in Both Human Benign and Malignant Uterine Soft Tissue Tumors
PLoS One , 2012; 7(6):e40015. Epub 2012 Jun 29
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