Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000019875 (100%)
Mouse ENSMUSG00000037236 (100%)
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Validated in Western blot using relevant lysates (see Western blot application images above)
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS
Nat Commun , 2020 Oct 20; 11:5304. Epub 2020 Oct 20
ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export
Sci Rep , 2017 Nov 6; 7:14529. Epub 2017 Nov 6
Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis.
Nat Neurosci , 2014 May; 17(5):664-6. Epub 2014 Mar 30
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