Polyclonal Anti-LAMA4 Antibody
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000019846 (86%)
Rat ENSRNOG00000000599 (85%)
Recommended conditions:
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
All characterization data for ENSG00000112769 on the Human Protein Atlas
Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis
BMC Vet Res , 2020 Jun 22; 16:206. Epub 2020 Jun 22
Down-regulated LAMA4 inhibits oxidative stress-induced apoptosis of retinal ganglion cells through the MAPK signaling pathway in rats with glaucoma
Cell Cycle , 2019 Apr 19; 18(9):932-948. Epub 2019 Apr 19
MCAM and LAMA4 are highly enriched in tumor blood vessels of renal cell carcinoma and predict patient outcome
Cancer Res , 2016 Feb 26; 76(8):2314-2326. Epub 2016 Feb 26
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