Polyclonal Anti-KNSTRN Antibody

kinetochore-localized astrin/SPAG5 binding protein
Recommended Applications
Product Description
Polyclonal Antibody against Human KNSTRN
Alternative Gene Names
C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1
Product Number
Unit Size
Lot dependent
>10 in Stock
Ready to Ship
Target Protein
kinetochore-localized astrin/SPAG5 binding protein
Target Gene
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
Verified Species Reactivity
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000027331 (66%)

Rat ENSRNOG00000009334 (64%)

40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:1000 - 1:2500

Retrieval method: HIER pH6

Immunofluorescence in Cell Lines (ICC-IF)

Recommended conditions:

Fixation/Permeabilization: PFA/Triton X-100

Working concentration: 0.25-2 µg/ml

Protein Name
kinetochore-localized astrin/SPAG5 binding protein
Gene Name
Alternative Gene Names
C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Normally shipped at ambient temperature
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000128944 on the Human Protein Atlas

Ferrandiz N, Downie L, Starling GP, Royle SJ

Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes

J Cell Biol , 2022 Apr 29; 221(6):e202203021. Epub 2022 Apr 29

PubMed ID: 35486148 DOI: 10.1083/jcb.202203021

Song X, Conti D, Shrestha RL, Braun D, Draviam VM

Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation

Nat Commun , 2021 Dec 1; 12:7010. Epub 2021 Dec 1

PubMed ID: 34853300 DOI: 10.1038/s41467-021-27131-9

Conti D, Gul P, Islam A, Martín-Durán JM, Pickersgill RW, Draviam VM

Kinetochores attached to microtubule-ends are stabilised by Astrin bound PP1 to ensure proper chromosome segregation

eLife , 2019 Dec 6; 8:e49325. Epub 2019 Dec 6

PubMed ID: 31808746 DOI: 10.7554/eLife.49325

Shrestha RL, Conti D, Tamura N, Braun D, Ramalingam RA, Cieslinski K, Ries J, Draviam VM

Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells

Nat Commun , 2017 Jul 28; 8:150. Epub 2017 Jul 28

PubMed ID: 28751710 DOI: 10.1038/s41467-017-00209-z

Chung HJ, Park JE, Lee NS, Kim H, Jang CY

Phosphorylation of Astrin Regulates Its Kinetochore Function

J Biol Chem , 2016 Jun 20; 291(34):17579-17592. Epub 2016 Jun 20

PubMed ID: 27325694 DOI: 10.1074/jbc.M115.712745

Tamura N, Simon JE, Nayak A, Shenoy R, Hiroi N, Boilot V, Funahashi A, Draviam VM

A proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset

Biol Open , 2015 Jan 16; 4(2):155-169. Epub 2015 Jan 16

PubMed ID: 25596275 DOI: 10.1242/bio.201410413

Shrestha RL, Draviam VM

Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK

Curr Biol , 2013 Aug 19; 23(16):1514-1526

PubMed ID: 23891108 DOI: 10.1016/j.cub.2013.06.040

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Join the Explorer Program

Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.

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Corresponding Antigens


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