Anti-KMT2D Antibody


Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000048154 (90%)
Rat ENSRNOG00000061499 (84%)
Recommended conditions:
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
Recommended conditions:
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
All characterization data for ENSG00000167548 on the Human Protein Atlas
PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression
Cell Rep , 2019 Apr 2; 27(1):294-306.e5
KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary
Nat Commun , 2018 Jun 27; 9:2496. Epub 2018 Jun 27
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis
Genes Dev , 2018 Jan 15; 32(2):181-193
Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis
Nat Med , 2015 Sep 14; 21(10):1190-1198. Epub 2015 Sep 14
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma
Acta Neuropathol , 2013 Mar; 125(3):373-384. Epub 2012 Nov 25
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