Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000016299 (89%)
Mouse ENSMUSG00000003032 (89%)
Dilution: 1:1000 - 1:2500
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
Recombinant expression validation in WB using target protein overexpression.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Inhibition of Epstein-Barr Virus Replication in Human Papillomavirus-Immortalized Keratinocytes
J Virol , 2019 Jan 4; 93(2):e01216-18. Epub 2019 Jan 4
KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
Nat Med , 2017 Sep 18; 23(10):1176-1190. Epub 2017 Sep 18
BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice
Development , 2017 Jul 15; 144(14):2560-2569
Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality
Development , 2016 Dec 1; 143(23):4368-4380
Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells
PLoS Pathog , 2015 Oct; 11(10):e1005195. Epub 2015 Oct 2
ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes
Genes Dev , 2014 Sep 15; 28(18):2013-2026
Endothelial Krüppel-like Factor 4 Regulates Angiogenesis and the Notch Signaling Pathway
J Biol Chem , 2014 Apr 25; 289(17):12016-12028. Epub 2014 Mar 5
A study of embryonic stem cell-related proteins in human astrocytomas: identification of Nanog as a predictor of survival.
Int J Cancer , 2014 Mar 1; 134(5):1123-31. Epub 2013 Sep 16
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