Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000048944 (56%)
Mouse ENSMUSG00000025492 (56%)
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Validated in Western blot using relevant lysates (see Western blot application images above)
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Interferon-Induced Transmembrane Protein 1 Restricts Replication of Viruses That Enter Cells via the Plasma Membrane
J Virol , 2019 Mar 5; 93(6):e02003-18. Epub 2019 Mar 5
Expression of IFITM1 as a prognostic biomarker in resected gastric and esophageal adenocarcinoma
Biomark Res , 2016 May 14; 4:10. Epub 2016 May 14
Targeted development of specific biomarkers of endometrial stromal cell differentiation using bioinformatics: the IFITM1 model.
Mod Pathol , 2014 Apr; 27(4):569-79. Epub 2013 Sep 27
In Vivo Functional Requirement of the Mouse Ifitm1 Gene for Germ Cell Development, Interferon Mediated Immune Response and Somitogenesis
PLoS One , 2012; 7(10):e44609. Epub 2012 Oct 24
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