Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000039997 (53%)
Rat ENSRNOG00000003480 (39%)
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells
PLoS Pathog , 2019 Jul 1; 15(7):e1007883. Epub 2019 Jul 1
Tumor cell-specific AIM2 regulates growth and invasion of cutaneous squamous cell carcinoma
Oncotarget , 2017 May 2; 8(28):45825-45836. Epub 2017 May 2
Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses
PLoS Pathog , 2016 Oct 20; 12(10):e1005967. Epub 2016 Oct 20
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