Polyclonal Anti-HTR2B Antibody
Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000026228 (77%)
Rat ENSRNOG00000017625 (77%)
Dilution: 1:500 - 1:1000
Retrieval method: HIER pH6
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Genomic landscape and expression profile of consensus molecular subtype four of colorectal cancer
Front Immunol , 2023 Jun 19; 14:1160052. Epub 2023 Jun 19
Molecular and clinicopathological differences between depressed and protruded T2 colorectal cancer
PLoS One , 2022 Oct 20; 17(10):e0273566. Epub 2022 Oct 20
Fibroblast activation protein identifies Consensus Molecular Subtype 4 in colorectal cancer and allows its detection by 68Ga-FAPI-PET imaging
Br J Cancer , 2022 Mar 16; 127(1):145-155. Epub 2022 Mar 16
PD-L1 as a Prognostic Factor in Early-Stage Colon Carcinoma within the Immunohistochemical Molecular Subtype Classification
Cancers (Basel) , 2021 Apr 17; 13(8):1943. Epub 2021 Apr 17
Immunohistochemistry‐Based Consensus Molecular Subtypes as a Prognostic and Predictive Biomarker for Adjuvant Chemotherapy in Patients with Stage II Colorectal Cancer
Oncologist , 2020 Sep 28; 25(12):e1968-e1979. Epub 2020 Sep 28
Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes
PLoS One , 2019 Feb 20; 14(2):e0211477. Epub 2019 Feb 20
Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion
Oncogene , March 21, 2016
Human Polyomavirus Receptor Distribution in Brain Parenchyma Contrasts with Receptor Distribution in Kidney and Choroid Plexus
Am J Pathol , 2015 Jun 6; 185(8):2246-2258
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.
Nat Med , 2013 May; 19(5):614-8. Epub 2013 Apr 14
Join the Explorer Program
Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.