Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000026228 (77%)
Rat ENSRNOG00000017625 (77%)
Dilution: 1:500 - 1:1000
Retrieval method: HIER pH6
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Early-stage serrated adenocarcinomas are divided into several molecularly distinct subtypes
PLoS One , 2019 Feb 20; 14(2):e0211477. Epub 2019 Feb 20
Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion
Oncogene , March 21, 2016
Human Polyomavirus Receptor Distribution in Brain Parenchyma Contrasts with Receptor Distribution in Kidney and Choroid Plexus
Am J Pathol , 2015 Jun 6; 185(8):2246-2258
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.
Nat Med , 2013 May; 19(5):614-8. Epub 2013 Apr 14
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