Polyclonal Anti-HSD17B12 Antibody

hydroxysteroid (17-beta) dehydrogenase 12
References (2)
Recommended Applications
Product Description
Polyclonal Antibody against Human HSD17B12
Alternative Gene Names
KAR, SDR12C1
Open Datasheet
Price
$505.00
Product Number
HPA016427
Unit Size
Concentration
Lot dependent
Availability
>10 in Stock
Ships
Ready to Ship
Show all images
[4 pictures]
Immunohistochemical staining of human testis shows strong cytoplasmic positivity in Leydig cells.

Additional Images

See additional IHC images using this antibody for 44 normal tissues and 20 cancers on the Human Protein Atlas
Target Protein
hydroxysteroid (17-beta) dehydrogenase 12
Target Gene
HSD17B12
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
WGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLD
Verified Species Reactivity
Human
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000027195 (83%)

Rat ENSRNOG00000009630 (83%)

Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Buffer
40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Concentration
Product Data Sheet
Download data sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:50 - 1:200

Retrieval method: HIER pH6

Protocols
View all protocols
Protein Name
hydroxysteroid (17-beta) dehydrogenase 12
Gene Name
HSD17B12
Alternative Gene Names
KAR, SDR12C1
UniProt ID
Q53GQ0
Gene (Ensembl)
ENSG00000149084
Entrez Gene ID
Entrez gene: 51144
Shipping
Normally shipped at ambient temperature
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000149084 on the Human Protein Atlas

Tsachaki M, Strauss P, Dunkel A, Navrátilová H, Mladenovic N, Odermatt A

Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration

Cell Mol Life Sci , 2019 Jul 13; 77(6):1153-1175. Epub 2019 Jul 13

PubMed ID: 31302749 DOI: 10.1007/s00018-019-03227-w

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Join the Explorer Program

Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.

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Corresponding Antigens
PrEST Antigen HSD17B12 (APrEST73031)

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