Anti-HSCB Antibody

HscB mitochondrial iron-sulfur cluster co-chaperone
Recommended Applications
Product Description
Polyclonal Antibody against Human HSCB
Alternative Gene Names
DNAJC20, HSC20, Jac1
Product Number
Unit Size
Lot dependent
>10 in Stock
Ready to Ship
Target Protein
HscB mitochondrial iron-sulfur cluster co-chaperone
Target Gene
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
Verified Species Reactivity
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000043510 (81%)

Rat ENSRNOG00000037508 (79%)

40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact for more information.
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:200 - 1:500

Retrieval method: HIER pH6

Protein Name
HscB mitochondrial iron-sulfur cluster co-chaperone
Gene Name
Alternative Gene Names
DNAJC20, HSC20, Jac1
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Normally shipped at ambient temperature
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000100209 on the Human Protein Atlas

Liu G, Sil D, Maio N, Tong WH, Bollinger JM Jr, Krebs C, Rouault TA

Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase

Nat Commun , 2020 Dec 9; 11:6310. Epub 2020 Dec 9

PubMed ID: 33298951 DOI: 10.1038/s41467-020-20145-9

Ferecatu I, Canal F, Fabbri L, Mazure NM, Bouton C, Golinelli-Cohen MP

Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation

PLoS One , 2018 Mar 29; 13(3):e0194782. Epub 2018 Mar 29

PubMed ID: 29596470 DOI: 10.1371/journal.pone.0194782

Ferecatu I, Gonçalves S, Golinelli-Cohen MP, Clémancey M, Martelli A, Riquier S, Guittet E, Latour JM, Puccio H, Drapier JC, Lescop E, Bouton C

The Diabetes Drug Target MitoNEET Governs a Novel Trafficking Pathway to Rebuild an Fe-S Cluster into Cytosolic Aconitase/Iron Regulatory Protein 1

J Biol Chem , 2014 Oct 10; 289(41):28070-28086. Epub 2014 Jul 10

PubMed ID: 25012650 DOI: 10.1074/jbc.M114.548438

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Alternative Antibodies
Corresponding Antigens


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