Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000059325 (74%)
Rat ENSRNOG00000024689 (74%)
Dilution: 1:2500 - 1:5000
Retrieval method: HIER pH6
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain
eLife , 2020 Apr 21; 9:e54873. Epub 2020 Apr 21
Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex
eLife , 2019 Dec 3; 8:e49376. Epub 2019 Dec 3
Individual brain organoids reproducibly form cell diversity of the human cerebral cortex
Nature , 2019 Jun 5; 570(7762):523-527. Epub 2019 Jun 5
The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice
eLife , 2016 Aug 9; 5:e18197. Epub 2016 Aug 9
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells.
Nat Methods , 2013 Apr; 10(4):315-23. Epub 2013 Feb 24
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