Dilution: 1:1000 - 1:2500
Retrieval method: HIER pH6
Working concentration: 0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 1-4 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Validated in Western blot using relevant lysates (see Western blot application images above)
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor
Cancer Med , 2018 Aug 14; 7(9):4744-4754. Epub 2018 Aug 14
Investigation of HNF-1B as a diagnostic biomarker for pancreatic ductal adenocarcinoma
Biomark Res , 2018 Jul 27; 6:25. Epub 2018 Jul 27
Caudal migration and proliferation of renal progenitors regulates early nephron segment size in zebrafish
Sci Rep , 2016 Oct 19; 6:35647. Epub 2016 Oct 19
Prognostic relevance of molecular subtypes and master regulators in pancreatic ductal adenocarcinoma
BMC Cancer , 2016 Aug 12; 16:632. Epub 2016 Aug 12
Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells
PLoS One , 2016 May 19; 11(5):e0154912. Epub 2016 May 19
Molecular analysis of mixed endometrial carcinomas shows clonality in most cases
Am J Surg Pathol , 2016 Feb; 40(2):166-180
Dissection of transcriptional and cis‐regulatory control of differentiation in human pancreatic cancer
EMBO J , 2016 Jan 14; 35(6):595-617. Epub 2016 Jan 14
Long-term primary culture of a clear cell ovarian carcinoma reveals an epithelial–mesenchymal cooperative interaction
Cancer Cell Int , 2015; 15:88. Epub 2015 Sep 24
Hepatocyte nuclear factor-1β is not a specific marker of clear cell carcinoma in serous effusions.
Cancer Cytopathol , 2014 Feb; 122(2):153-8
Role of PINCH and Its Partner Tumor Suppressor Rsu-1 in Regulating Liver Size and Tumorigenesis
PLoS One , 2013; 8(9):e74625. Epub 2013 Sep 18
Genomic profiling of papillary renal cell tumours identifies small regions of DNA alterations: a possible role of HNF1B in tumour development.
Histopathology , 2011 May; 58(6):934-43. Epub 2011 Mar 25
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