Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence
J Cell Mol Med , 2019 Nov 20; 24(1):276-284. Epub 2019 Nov 20
Interactions Between ABCB1 Genotype and Preoperative Statin Use Impact Clinical Outcomes Among Breast Cancer Patients
Front Oncol , 2018 Oct 12; 8:428. Epub 2018 Oct 12
Cilia loss sensitizes cells to transformation by activating the mevalonate pathway
J Exp Med , 2018 Jan 2; 215(1):177-195
Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study
Br J Cancer , 2017 May 18; 116(12):1652-1659. Epub 2017 May 18
HMG-CoAR expression in male breast cancer: relationship with hormone receptors, Hippo transducers and survival outcomes
Sci Rep , 2016 Oct 7; 6:35121. Epub 2016 Oct 7
High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer
Oncotarget , 2016 Jul 21; 7(37):59640-59651. Epub 2016 Jul 21
Tumor-specific expression of HMG-CoA reductase in a population-based cohort of breast cancer patients
BMC Clin Pathol , 2015; 15:8. Epub 2015 May 20
HMG-CoA reductase expression in primary colorectal cancer correlates with favourable clinicopathological characteristics and an improved clinical outcome
Diagn Pathol , 2014 Apr 7; 9:78. Epub 2014 Apr 7
Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial.
Breast Cancer Res Treat , 2013 Apr; 138(2):499-508. Epub 2013 Mar 8
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