Polyclonal Anti-GSDMD Antibody
Human Protein Atlas
Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000007728 (63%)
Mouse ENSMUSG00000022575 (61%)
Working concentration: 0.04-0.4 µg/ml
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages
Cell Death Discov , 2021 Oct 30; 7:327. Epub 2021 Oct 30
Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
Cell Rep , 2021 Apr 13; 35(2):108998
Human polymorphisms in GSDMD alter the inflammatory response
J Biol Chem , 2020 Jan 27; 295(10):3228-3238. Epub 2020 Jan 27
Join the Explorer Program
Are you using our products in an application or species we have not yet tested? Why not participate in the Explorer Program, and we will show your contribution here. If you would like to share your results with us, the Explorer Program offers a 25µl vial free of charge with your next order.