Enhanced Validation

Anti-FYN Antibody

FYN proto-oncogene, Src family tyrosine kinase
Recommended Applications
Genetic validation in WB by siRNA knockdown.
Product Description
Polyclonal Antibody against Human FYN
Alternative Gene Names
MGC45350, SLK, SYN
Product Number
Unit Size
100 µl
Lot dependent
10 in Stock
Ready to Ship
Target protein
FYN proto-oncogene, Src family tyrosine kinase
Target gene
Antigen sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
Verified Species Reactivity
Human, Mouse, Rat
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Rat ENSRNOG00000000596 (100%)

Mouse ENSMUSG00000019843 (100%)

40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification method
Affinity purified using the PrEST antigen as affinity ligand
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Lot dependent
Unit Size
100 µl
Lot dependent
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:50 - 1:200

Retrieval method: HIER pH6

Western Blot (WB)

Recommended conditions:

Working concentration: 0.4 µg/ml

Immunofluorescence in cell lines (ICC-IF)

Recommended conditions:

Fixation/Permeabilization: PFA/Triton X-100

Working concentration: 1-4 µg/ml

Western Blot (WB)

Genetic validation in WB by siRNA knockdown.

Protein Name
FYN proto-oncogene, Src family tyrosine kinase
Gene Name
Alternative Gene Names
MGC45350, SLK, SYN
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Normally shipped at ambient temperature
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000010810 on the Human Protein Atlas

Li J, Rong MH, Dang YW, He RQ, Lin P, Yang H, Li XJ, Xiong DD, Zhang LJ, Qin H, Feng CX, Chen XY, Zhong JC, Ma J, Chen G

Differentially expressed gene profile and relevant pathways of the traditional Chinese medicine cinobufotalin on MCF-7 breast cancer cells

Mol Med Rep , 2019 Mar 19; 19(5):4256-4270. Epub 2019 Mar 19

PubMed ID: 30896874 DOI: 10.3892/mmr.2019.10062

Suo M, Wang P, Zhang M

Role of Fyn-mediated NMDA receptor function in prediabetic neuropathy in mice

J Neurophysiol , 2016 May 4; 116(2):448-455. Epub 2016 May 4

PubMed ID: 27146985 DOI: 10.1152/jn.00229.2016

Lau DH, Hogseth M, Phillips EC, O’Neill MJ, Pooler AM, Noble W, Hanger DP

Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease

Acta Neuropathol Commun , 2016 May 18; 4:49. Epub 2016 May 18

PubMed ID: 27193083 DOI: 10.1186/s40478-016-0317-4

Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, Ito A, Ogata T, Terada N, Tanoue A, Yamauchi J

Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination

Mol Biol Cell , 2015 Oct 1; 26(19):3489-3503

PubMed ID: 26224309 DOI: 10.1091/mbc.E14-05-1020

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Alternative Antibodies
Corresponding Antigens


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