Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000029581 (96%)
Rat ENSRNOG00000056585 (63%)
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Validation of protein expression in IHC by comparing independent antibodies targeting different epitopes of the protein.
Validated against independent antibody Anti-FSCN1 HPA050654.
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Fascin-1 is released from proximal tubular cells in response to calcineurin inhibitors (CNIs) and correlates with isometric vacuolization in kidney transplanted patients
Am J Transl Res , 2017 Sep 15; 9(9):4173-4183. Epub 2017 Sep 15
Studying the role of fascin-1 in mechanically stressed podocytes
Sci Rep , 2017 Aug 30; 7:9916. Epub 2017 Aug 30
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