Enhanced Validation

Anti-FOXC1 Antibody

forkhead box C1
Recommended Applications
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Product Description
Polyclonal Antibody against Human FOXC1
Alternative Gene Names
ARA, FKHL7, FREAC3, IGDA, IHG1, IRID1
Price
$445.00
Product Number
HPA040670
Unit Size
Concentration
Lot dependent
Availability
>10 in Stock
Ships
Ready to Ship
Target Protein
forkhead box C1
Target Gene
FOXC1
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
YPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPSSQSLYRTSGAFVYDCSKF
Verified Species Reactivity
Human
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Rat ENSRNOG00000017800 (98%)

Mouse ENSMUSG00000050295 (98%)

Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Buffer
40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Concentration
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:50 - 1:200

Retrieval method: HIER pH6

Immunofluorescence in Cell Lines (ICC-IF)

Recommended conditions:

Fixation/Permeabilization: PFA/Triton X-100

Working concentration: 0.25-2 µg/ml

Protocols
Immunohistochemistry (IHC)

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

Protein Name
forkhead box C1
Gene Name
FOXC1
Alternative Gene Names
ARA, FKHL7, FREAC3, IGDA, IHG1, IRID1
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Shipping
Normally shipped at ambient temperature
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000054598 on the Human Protein Atlas

Hirukawa A, Smith HW, Zuo D, Dufour CR, Savage P, Bertos N, Johnson RM, Bui T, Bourque G, Basik M, Giguère V, Park M, Muller WJ

Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

Nat Commun , 2018 Jun 29; 9:2547. Epub 2018 Jun 29

PubMed ID: 29959321 DOI: 10.1038/s41467-018-04864-8

Wang L, Chai L, Ji Q, Cheng R, Wang J, Han S

Forkhead box protein C1 promotes cell proliferation and invasion in human cervical cancer

Mol Med Rep , 2018 Jan 11; 17(3):4392-4398. Epub 2018 Jan 11

PubMed ID: 29328384 DOI: 10.3892/mmr.2018.8423

DeGraff DJ, Grabowska MM, Case T, Yu X, Herrick MK, Hayward W, Strand DW, Cates JM, Hayward SW, Gao N, Walter MA, Buttyan R, Yi Y, Kaestner KH, Matusik RJ

Foxa1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype

Lab Invest , 2014 Jul; 94(7):726-739. Epub 2014 May 19

PubMed ID: 24840332 DOI: 10.1038/labinvest.2014.64

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Corresponding Antigens

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