Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000007281 (99%)
Mouse ENSMUSG00000068699 (99%)
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Novel Mutation in FLNC (Filamin C) Causes Familial Restrictive Cardiomyopathy
Circ Cardiovasc Genet , 2017 Dec; 10(6):e001780
Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice
J Clin Invest , 2017 Sep 5; 127(10):3730-3740. Epub 2017 Sep 5
Spatiotemporal Proteomic Profiling of Human Cerebral Development
Mol Cell Proteomics , 2017 Jul 7; 16(9):1548-1562. Epub 2017 Jul 7
FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy
JACC Basic Transl Sci , 2016 Jul 27; 1(5):344-359. Epub 2016 Jul 27
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