Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000001420 (96%)
Mouse ENSMUSG00000019054 (95%)
Dilution: 1:500 - 1:1000
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Gas7 knockout affects PINK1 expression and mitochondrial dynamics in mouse cortical neurons
FASEB Bioadv , 2020 Jan 21; 2(3):166-181. Epub 2020 Jan 21
Mitochondrial fragmentation affects neither the sensitivity to TNFα-induced apoptosis of Brucella-infected cells nor the intracellular replication of the bacteria
Sci Rep , 2018 Mar 26; 8:5173. Epub 2018 Mar 26
Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms
FEBS J , 2018 Jan 8; 285(3):481-500. Epub 2018 Jan 8
Skeletal Muscle Fibre-Specific Knockout of p53 Does Not Reduce Mitochondrial Content or Enzyme Activity
Front Physiol , 2017 Dec 4; 8:941. Epub 2017 Dec 4
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain
Neurobiol Aging , 2016 Aug 18; 48:34-47. Epub 2016 Aug 18
Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts
Biosci Rep , 2013 Feb 7; 33(2):e00023. Epub 2013 Feb 7
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