Dilution: 1:5000 - 1:10000
Retrieval method: HIER pH6
Working concentration: 0.4 µg/ml
Orthogonal validation of protein expression using WB by comparison to RNA-seq data of corresponding target in high and low expression cell lines.
Recombinant expression validation in WB using target protein overexpression.
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells
J Transl Med , 2018 Mar 14; 16:64. Epub 2018 Mar 14
Albumin-based nanoparticles as methylprednisolone carriers for targeted delivery towards the neonatal Fc receptor in glomerular podocytes
Int J Mol Med , 2017 Feb 21; 39(4):851-860. Epub 2017 Feb 21
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
Nature , 2014 Oct 30; 514(7524):642-645. Epub 2014 Aug 13
Neonatal Fc Receptor Expression in Dendritic Cells Mediates Protective Immunity Against Colorectal Cancer
Immunity , 2013 Dec 12; 39(6):1095-1107. Epub 2013 Nov 27
Robust expression of the human neonatal Fc receptor in a truncated soluble form and as a full-length membrane-bound protein in fusion with eGFP.
PLoS One , 2013; 8(11):e81350. Epub 2013 Nov 18
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