Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000040651 (90%)
Rat ENSRNOG00000014750 (90%)
Dilution: 1:50 - 1:200
Retrieval method: HIER pH6
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s
Nat Commun , 2020 Nov 3; 11:5387. Epub 2020 Nov 3
The first mouse mutants of D14Abb1e (Fam208a) show that it is critical for early development
Mamm Genome , 2014 Aug; 25(7-8):293-303. Epub 2014 Apr 30
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