Highest antigen sequence identity to the following orthologs:
Rat ENSRNOG00000014750 (66%)
Mouse ENSMUSG00000040651 (63%)
Dilution: 1:200 - 1:500
Retrieval method: HIER pH6
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
Nat Commun , 2020 Oct 2; 11:4940. Epub 2020 Oct 2
Periphilin self-association underpins epigenetic silencing by the HUSH complex
Nucleic Acids Res , 2020 Sep 25; 48(18):10313-10328. Epub 2020 Sep 25
Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection
Cell Rep , 2019 Apr 30; 27(5):1579-1596.e7. Epub 2019 Apr 30
HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells
Proc Natl Acad Sci U S A , 2019 Apr 24; 116(19):9568-9577. Epub 2019 Apr 24
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators
Nature , 2017 Dec 6; 553(7687):228-232. Epub 2017 Dec 6
Characterization of a core region in the A2UCOE that confers effective anti-silencing activity
Sci Rep , 2017 Aug 31; 7:10213. Epub 2017 Aug 31
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2
Nat Genet , 2017 Jun 5; 49(7):1035-1044. Epub 2017 Jun 5
GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells.
Science , 2015 Jun 26; 348(6242):1481-5
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