Highest antigen sequence identity to the following orthologs:
Mouse ENSMUSG00000062312 (82%)
Rat ENSRNOG00000006450 (81%)
Dilution: 1:500 - 1:1000
Retrieval method: HIER pH6
Working concentration: 0.04-0.4 µg/ml
Fixation/Permeabilization: PFA/Triton X-100
Working concentration: 0.25-2 µg/ml
Validated in Western blot using relevant lysates (see Western blot application images above)
This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.
In situ analysis of Her2 DNA and RNA in retinoblastoma and adjacent retina
Oncoscience , 2019 Aug 23; 6(7-8):357-366. Epub 2019 Aug 23
Site-specifically labeled 89Zr-DFO-trastuzumab improves immuno-reactivity and tumor uptake for immuno-PET in a subcutaneous HER2-positive xenograft mouse model
Theranostics , 2019 Jun 9; 9(15):4409-4420. Epub 2019 Jun 9
HER2 Overexpression in Retinoblastoma: A Potential Therapeutic Target?
Ocul Oncol Pathol , 2017 Feb 23; 3(3):210-215. Epub 2017 Feb 23
HER2/ERBB2 immunoreactivity in human retinoblastoma
Tumour Biol , 2015 Nov 27; 37(5):6135-6142. Epub 2015 Nov 27
The HER2-Encoded miR-4728-3p Regulates ESR1 through a Non-Canonical Internal Seed Interaction
PLoS One , 2014; 9(5):e97200. Epub 2014 May 14
Progesterone receptor negativity is an independent risk factor for relapse in patients with early stage endometrioid endometrial adenocarcinoma.
Gynecol Oncol , 2013 Sep; 130(3):463-9. Epub 2013 Jun 15
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