Anti-DIS3L Antibody

DIS3 like exosome 3'-5' exoribonuclease
Recommended Applications
Product Description
Polyclonal Antibody against Human DIS3L
Alternative Gene Names
DIS3L1, FLJ38088, KIAA1955, MGC4562
Product Number
Unit Size
Lot dependent
6 in Stock
Ready to Ship
Target Protein
DIS3 like exosome 3'-5' exoribonuclease
Target Gene
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
Verified Species Reactivity
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Rat ENSRNOG00000010537 (93%)

Mouse ENSMUSG00000032396 (91%)

40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact for more information.
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:200 - 1:500

Retrieval method: HIER pH6

Immunofluorescence in Cell Lines (ICC-IF)

Recommended conditions:

Fixation/Permeabilization: PFA/Triton X-100

Working concentration: 0.25-2 µg/ml

Protein Name
DIS3 like exosome 3'-5' exoribonuclease
Gene Name
Alternative Gene Names
DIS3L1, FLJ38088, KIAA1955, MGC4562
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Normally shipped at ambient temperature
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000166938 on the Human Protein Atlas

Kalisiak K, Kuliński TM, Tomecki R, Cysewski D, Pietras Z, Chlebowski A, Kowalska K, Dziembowski A

A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans

Nucleic Acids Res , 2016 Sep 26; 45(4):2068-2080. Epub 2016 Sep 26

PubMed ID: 28204585 DOI: 10.1093/nar/gkw862

Tomecki R, Drazkowska K, Kucinski I, Stodus K, Szczesny RJ, Gruchota J, Owczarek EP, Kalisiak K, Dziembowski A

Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target

Nucleic Acids Res , 2014 Jan; 42(2):1270-1290. Epub 2013 Oct 21

PubMed ID: 24150935 DOI: 10.1093/nar/gkt930

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Corresponding Antigens


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