Enhanced Validation

Anti-CYP11A1 Antibody

cytochrome P450, family 11, subfamily A, polypeptide 1
Recommended Applications
Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.
Product Description
Polyclonal Antibody against Human CYP11A1
Alternative Gene Names
CYP11A, P450SCC
Price
$445.00
Product Number
HPA016436
Unit Size
Concentration
Lot dependent
Availability
>10 in Stock
Ships
Ready to Ship
Target Protein
cytochrome P450, family 11, subfamily A, polypeptide 1
Target Gene
CYP11A1
Antigen Sequence
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence
RSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAA
Verified Species Reactivity
Human
Interspecies Information

Highest antigen sequence identity to the following orthologs:

Mouse ENSMUSG00000032323 (73%)

Rat ENSRNOG00000008074 (59%)

Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Buffer
40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Material Safety Data Sheet
Purification Method
Affinity purified using the PrEST antigen as affinity ligand
Notes
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Unit Size
100 µl
Current Lot
Produced on demand. Contact support@atlasantibodies.com for more information.
Concentration
Product Data Sheet
Immunohistochemistry (IHC)

Recommended conditions:

Dilution: 1:1000 - 1:2500

Retrieval method: HIER pH6

Protocols
Immunohistochemistry (IHC)

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

Protein Name
cytochrome P450, family 11, subfamily A, polypeptide 1
Gene Name
CYP11A1
Alternative Gene Names
CYP11A, P450SCC
UniProt ID
Gene (Ensembl)
Entrez Gene ID
Shipping
Normally shipped at ambient temperature
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Human Protein Atlas

This antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type. The results are part of an ongoing effort to map the human proteome using antibodies.

All characterization data for ENSG00000140459 on the Human Protein Atlas

Harpelunde Poulsen K, Nielsen JE, Frederiksen H, Melau C, Juul Hare K, Langhoff Thuesen L, Perlman S, Lundvall L, Mitchell RT, Juul A, Rajpert-De Meyts E, Jørgensen A

Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes

Hum Reprod , 2019 Nov 17; 34(11):2228-2243. Epub 2019 Nov 17

PubMed ID: 31734698 DOI: 10.1093/humrep/dez191

Melau C, Nielsen JE, Frederiksen H, Kilcoyne K, Perlman S, Lundvall L, Langhoff Thuesen L, Juul Hare K, Andersson AM, Mitchell RT, Juul A, Jørgensen A

Characterization of Human Adrenal Steroidogenesis During Fetal Development

J Clin Endocrinol Metab , 2018 Dec 21; 104(5):1802-1812. Epub 2018 Dec 21

PubMed ID: 30590593 DOI: 10.1210/jc.2018-01759

Gaudriault P, Mazaud-Guittot S, Lavoué V, Coiffec I, Lesné L, Dejucq-Rainsford N, Scholze M, Kortenkamp A, Jégou B

Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants

Environ Health Perspect , 2017 Aug 4; 125(8):087004. Epub 2017 Aug 4

PubMed ID: 28796631 DOI: 10.1289/EHP1014

Arboleda VA, Lee H, Parnaik R, Fleming A, Banerjee A, Ferraz-de-Souza B, Délot EC, Rodriguez-Fernandez IA, Braslavsky D, Bergadá I, Dell’Angelica EC, Nelson SF, Martinez-Agosto JA, Achermann JC, Vilain E

Mutations in the PCNA-binding domain of CDKN1C cause IMAGE Syndrome

Nat Genet , 2012 May 27; 44(7):788-792. Epub 2012 May 27

PubMed ID: 22634751 DOI: 10.1038/ng.2275

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Corresponding Antigens

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